This indicates an attack attempt against a Directory Traversal vulnerability in Trend Micro Control Manager.
The vulnerability is due to insufficient sanitizing of user supplied inputs in the application while handling maliciously crafted requests. A remote attacker can exploit this to upload arbitrary file to a targeted server via a crafted request.
Trend Micro Control Manager prior to Version 6.0 build 3444
System Compromise: Remote attackers can gain control of vulnerable systems.
Apply the most recent upgrade or patch from the vendor